Nanostructured Lipid Carriers: A potential drug carrier for cancer chemotherapy
نویسندگان
چکیده
منابع مشابه
Nanostructured Lipid Drug Carriers
solid lipid carriers – NLC. Particulate lipid matrices in the form of lipid pellets are known from the textbooks since many years, products are on the market (e. g. Mucosolvan retard, Boehringer-Ingelheim). After these lipid pellets as the first generation, P. Speiser developed so-called “lipid nanopellets for oral administration” in the middle of the eighties [1]. This system was not further d...
متن کاملNanostructured lipid carriers (NLCs): A Novel based nano carrier for drug delivery and drug targeting
Aim: Nano structured lipid carriers (NLCs) contains solid and liquid lipids as the significant principle in the drug delivery system. This review is focused on various aspects involved in the preparation, structure, advantages, limitations, types, physiochemical characterization and wide pharmaceutical applications of SLN has been explored. Method:It is revealed that NLCs proved to be a promisi...
متن کاملNanostructured lipid carriers: Promising drug delivery systems for future clinics.
During the past decade, the number of studies describing nanostructured lipid carriers (NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation is essentially due to defeated barriers within the technological process of lipid-based nanoparticles' formulation and increased knowledge of the underlying mechanisms of transport of NLCs via different routes of administ...
متن کاملLymph cancer chemotherapy: delivery of doxorubicin–gemcitabine prodrug and vincristine by nanostructured lipid carriers
PURPOSE Radiation and chemotherapy are the most common course of treatment for B-cell lymphoma. Doxorubicin (DOX), gemcitabine (GEM), and vincristine (VCR) are the commonly used antilymphoma chemotherapeutic drugs. The aim of this study is to construct a novel drug delivery system for the combination delivery of the three drugs on lymphoma. MATERIALS AND METHODS DOX-GEM prodrug was synthesize...
متن کامل1. Nanostructured lipid carrier for bioavailability enhancement
Nanostructred lipid carrier(NLC) is second generation drug carrier system having solid matrix at room temperature. This carrier system is made up of physiological, biodegradable and biocompatible lipid materials and surfactants and is accepted by regulatory authorities for application in different drug delivery system. The main objective of this review is to explore the role of NLCs system for ...
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ژورنال
عنوان ژورنال: Lipids in Health and Disease
سال: 2012
ISSN: 1476-511X
DOI: 10.1186/1476-511x-11-159